IMPURITIES AVAILABLE FOR 'Colistimethate Sodium'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Colistimethate Sodium. Colistimethate sodium is a cyclic polypeptide antibiotic and a prodrug of colistin, used primarily against multidrug-resistant Gram-negative bacteria. It is particularly effective against Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. The sodium form improves water solubility, making it suitable for intravenous, intramuscular, and inhalation administration. After administration, it is hydrolyzed to the active form, colistin, which disrupts bacterial cell membranes. Colistimethate is often reserved as a last-line therapy due to rising antimicrobial resistance. It is commonly used in severe hospital-acquired infections, ventilator-associated pneumonia, and chronic lung infections in cystic fibrosis. Dose adjustments are required in renal impairment to prevent accumulation. Major risks include nephrotoxicity and neurotoxicity, necessitating careful monitoring during therapy. Buy high quality Colistimethate Sodium from Omsynth Lifesciences.