IMPURITIES AVAILABLE FOR 'Ixazomib'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Ixazomib. Ixazomib is an oral proteasome inhibitor used in the treatment of multiple myeloma, often in combination with lenalidomide and dexamethasone. It works by inhibiting the 20S proteasome, a key enzyme complex responsible for degrading ubiquitinated proteins, leading to accumulation of misfolded proteins and apoptosis of malignant plasma cells. Ixazomib offers the advantage of oral administration compared to other proteasome inhibitors like bortezomib, improving patient convenience and compliance. It has good bioavailability and is rapidly absorbed, with reversible binding to the proteasome. Common side effects include nausea, diarrhea, thrombocytopenia, rash, and peripheral neuropathy. The drug is metabolized mainly by CYP3A and eliminated via fecal and renal routes. Ixazomib represents an important advance in oral proteasome inhibitor therapy for relapsed or refractory multiple myeloma. Buy high quality Ixazomib from Omsynth Lifesciences.