Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Letermovir. Letermovir is an antiviral medication used for the prevention of cytomegalovirus (CMV) infection and disease in CMV-seropositive adult recipients of allogeneic hematopoietic stem cell transplants (HSCT). It works by inhibiting the CMV DNA terminase complex (UL56 subunit), which is essential for viral DNA processing and packaging, thereby blocking viral replication. Letermovir is available in oral and intravenous formulations and is notable for its unique mechanism of action, distinct from other antivirals like ganciclovir. It is well tolerated, with common side effects including nausea, diarrhea, and peripheral edema. The drug exhibits favorable safety and resistance profiles, with minimal hematologic toxicity. Letermovir is primarily metabolized by UGT1A1 and CYP3A4 enzymes and is a substrate for transport proteins such as OATP1B1/3. It represents a major advance in CMV prophylaxis for immunocompromised patients. Buy high quality Letermovir from Omsynth Lifesciences.
