IMPURITIES AVAILABLE FOR 'Mertansine'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Mertansine. Mertansine (DM1) is a potent cytotoxic maytansinoid derivative used as a microtubule inhibitor in antibody–drug conjugates (ADCs) for targeted cancer therapy. It works by binding to tubulin, disrupting microtubule assembly, and thereby inhibiting cell division, leading to apoptosis of rapidly proliferating tumor cells. Mertansine itself is too toxic for standalone use, but when linked to monoclonal antibodies (such as trastuzumab in trastuzumab emtansine or T-DM1), it selectively targets cancer cells expressing specific antigens, minimizing systemic toxicity. It is highly effective against HER2-positive breast cancer and other solid tumors. The drug’s antimitotic mechanism provides strong antitumor potency at low concentrations. Common side effects include fatigue, thrombocytopenia, and elevated liver enzymes. Overall, Mertansine is a key payload molecule in ADC-based oncology treatments, offering precision cytotoxicity with reduced systemic effects. Buy high quality Mertansine from Omsynth Lifesciences.