IMPURITIES AVAILABLE FOR 'Nilotinib Hydrochloride'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Nilotinib Hydrochloride. Nilotinib hydrochloride is a tyrosine kinase inhibitor (TKI) used in the treatment of Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML). It works by selectively inhibiting the BCR-ABL tyrosine kinase, the abnormal enzyme responsible for uncontrolled leukemic cell proliferation. Nilotinib binds to the inactive conformation of the BCR-ABL protein, blocking downstream signaling pathways involved in cell growth and survival. It is administered orally, usually twice daily on an empty stomach. The drug is metabolized primarily by CYP3A4 and has potential interactions with other medications affecting this enzyme. Common adverse effects include rash, pruritus, headache, nausea, and elevated liver enzymes. Serious risks involve QT prolongation, cardiovascular events, and pancreatitis. Regular cardiac and hepatic monitoring is recommended during therapy. Buy high quality Nilotinib Hydrochloride from Omsynth Lifesciences.