IMPURITIES AVAILABLE FOR 'Nisoldipine'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Nisoldipine. Nisoldipine is a dihydropyridine calcium channel blocker used primarily for the management of hypertension and angina pectoris. It works by inhibiting L-type calcium channels in vascular smooth muscle, leading to vasodilation, reduced peripheral resistance, and decreased blood pressure. Nisoldipine has a greater selectivity for vascular smooth muscle than cardiac tissue, minimizing negative inotropic effects. It is administered orally, typically in extended-release formulations to provide long-lasting blood pressure control. The drug is extensively metabolized by CYP3A4 in the liver and should not be taken with strong enzyme inhibitors like grapefruit juice. Common side effects include flushing, headache, dizziness, palpitations, and peripheral edema. It should be used cautiously in patients with severe aortic stenosis or heart failure. Nisoldipine effectively improves coronary blood flow and reduces cardiac workload. Buy high quality Nisoldipine from Omsynth Lifesciences.