IMPURITIES AVAILABLE FOR 'Pyrazinamide'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Pyrazinamide. Pyrazinamide is a first-line antitubercular drug used in combination therapy for the treatment of active tuberculosis, particularly during the initial intensive phase. It acts as a prodrug, converted by mycobacterial pyrazinamidase into pyrazinoic acid, which disrupts mycobacterial membrane transport and fatty acid synthesis, especially in acidic environments such as those within macrophages. Pyrazinamide is effective against semi-dormant Mycobacterium tuberculosis, helping shorten the overall treatment duration. It is well absorbed orally, widely distributed, and metabolized in the liver. Common side effects include hepatotoxicity, hyperuricemia, arthralgia, and gastrointestinal upset. Dose adjustments are required in hepatic impairment and in some cases of renal dysfunction. Pyrazinamide remains a critical component of modern TB treatment regimens. Buy high quality Pyrazinamide from Omsynth Lifesciences.