IMPURITIES AVAILABLE FOR 'Rolapitant'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Rolapitant. Rolapitant is a selective neurokinin-1 (NK1) receptor antagonist used to prevent delayed chemotherapy-induced nausea and vomiting (CINV). It blocks the action of substance P in the central nervous system, reducing emetic signaling pathways. Rolapitant has a long half-life (~180 hours), allowing single-dose administration per chemotherapy cycle. It is typically used in combination with 5-HT3 antagonists and corticosteroids for optimal antiemetic protection. The drug does not inhibit or induce CYP3A4, reducing potential drug interactions compared with some other NK1 antagonists. Common side effects include neutropenia, hiccups, fatigue, and gastrointestinal disturbances. It is available as both oral tablets and an intravenous formulation. Rolapitant helps enhance patient comfort and adherence during emetogenic chemotherapy. Buy high quality Rolapitant from Omsynth Lifesciences.