IMPURITIES AVAILABLE FOR 'Rolapitant Hydrochloride Hydrate'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Rolapitant Hydrochloride Hydrate. Rolapitant hydrochloride hydrate is the hydrated salt form of rolapitant, a highly selective neurokinin-1 (NK1) receptor antagonist used to prevent delayed chemotherapy-induced nausea and vomiting (CINV). It blocks substance P from binding to NK1 receptors in the brain, reducing emetic signaling. The hydrochloride hydrate form improves stability and formulation properties for oral administration. Its exceptionally long half-life (~180 hours) enables single-dose use per chemotherapy cycle. It is typically combined with 5-HT3 antagonists and corticosteroids for comprehensive antiemetic protection. Unlike some NK1 antagonists, it does not affect CYP3A4, minimizing drug interaction risks. Common adverse effects include neutropenia, hiccups, dizziness, and gastrointestinal upset. The drug enhances patient comfort by reducing delayed-phase nausea associated with highly emetogenic chemotherapy. Buy high quality Rolapitant Hydrochloride Hydrate from Omsynth Lifesciences.