IMPURITIES AVAILABLE FOR 'Saquinavir'

Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Saquinavir. Saquinavir is a first-generation HIV-1 protease inhibitor used in combination antiretroviral therapy (cART). It blocks the viral protease enzyme required for processing gag-pol polyproteins, resulting in the production of immature, noninfectious virions. Due to low oral bioavailability, it is commonly coadministered with ritonavir to boost plasma levels through CYP3A4 inhibition. Saquinavir is effective against HIV-1 when used as part of a multidrug regimen, helping reduce viral load and increase CD4 counts. It is available in hard-gel and soft-gel capsule formulations, though the latter offers better absorption. Common adverse effects include gastrointestinal discomfort, nausea, and abdominal pain. It may cause QT and PR interval prolongation, requiring caution in patients with cardiac risk factors. Drug interactions are significant due to CYP3A4 metabolism. Saquinavir played a major role in early protease inhibitor–based HIV therapy. Buy high quality Saquinavir from Omsynth Lifesciences.