IMPURITIES AVAILABLE FOR 'Teneligliptin Hydrobromide Hydrate'
Omsynth Lifesciences Pvt. Ltd. is one of the leading manufacturer and exporter of Teneligliptin Hydrobromide Hydrate. Teneligliptin hydrobromide hydrate is a hydrated salt form of the DPP-4 inhibitor teneligliptin, used to treat type 2 diabetes mellitus. It enhances incretin activity by inhibiting DPP-4, leading to increased GLP-1 and GIP levels, improved insulin secretion, and reduced glucagon release in a glucose-dependent manner. The hydrate form provides stability and optimal solubility for pharmaceutical formulations. Teneligliptin’s unique anchor-lock structure confers strong DPP-4 binding and sustained enzymatic inhibition. It effectively lowers HbA1c as monotherapy or in combination therapies. The drug is metabolized mainly through CYP3A4 and FMO3 pathways, allowing safe use even in renal impairment. It is generally well tolerated with mild adverse effects such as headache and nasopharyngitis. Hypoglycemia risk is low unless combined with insulin or sulfonylureas. Once-daily dosing supports good patient compliance. Buy high quality Teneligliptin Hydrobromide Hydrate from Omsynth Lifesciences.
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